Chuck Aryeetey

Hard working and dedicated BSc (Hons) Pharmacy graduate with significant experience in pharmaceutical care. Offers extensive leadership experience, solid organizational skills, and innovative thinking to advance the development of health in current and future generations.

Seeks to expand academic and research experience in pharmaceutical science by identifying health issues and combining theory, existing evidence, and scientific methods and processes to develop innovative solutions to key neuro-disorders.

• Date of Birth: 04/23/98
• Gender: Male
• Nationality: Ghanaian

• Public Speaker - Good public speaking skills obtained through presenting at the Trust Hospital as a clinical Pharmacist. Dementia and diabetes: a patient case and review of antidiabetic medications.
• Good writing skills through my experience in academic writing.

• Health Committee President,
• Collaborated with a 15-member team to develop a strategy for creating health awareness.
• Collaborated with the National Blood Services Ghana and University of Ghana Hospital to organize free health screening exercises for students.

• 06/02/22, Current, Accra, Research Assistant
• Conducted experimental studies to evaluate the effects of pharmacological agents on cognitive functions in dementia, using established animal models such as the Y-maze test and the novelty object recognition test to assess learning and memory.
• Analyzed and interpreted data on cognitive performance, contributing to the understanding of how various substances, including nootropics and antioxidants, influence neuroplasticity and mitigate cognitive impairments associated with dementia.
• A Retrospective Study of Mother-to-Child Transmission of Hepatitis B Among Pregnant Women: Risk Factors, Preventive Measures, and Health Outcomes at The Trust Hospital
• Literature review on the modulation of synaptic transmission in the context of pain and learning and memory in Medicinal Leeches

• 09/14/20, 09/14/22, Accra, Public Health Educator
• Collaborated with a 10-member team to educate about 100 children on online health literacy., Participated in free health screening exercise for 150+ market women and commercial drivers., Educated 300+ adolescents on sexually transmitted diseases, causes and ways to prevent them.

• 10/12/22, 10/15/22, Accra, COVID-19 Antigen Tester
• Administered and interpreted COVID-19 symptoms tests, including thermometer scans and surveys, to over 200 participants., Reported positive and negative response cases according to established protocols and reporting mandates., Maintained strict aseptic fields when collecting biological samples, minimizing staff and patient infection risk.

08/01/19, 05/10/20

1. Effects of Ascorbic Acid and Alpha-Tocopherol in experimental models of Ketamine-Induced Cognitive Impairment 

Background: Cognitive dysfunction, manifesting as learning and memory impairment, is prevalent in chronic diseases such as depression, epilepsy, and Alzheimer's disease, and can also occur without any known medical condition. Citicoline, an intermediate in phosphatidylcholine biosynthesis, has shown beneficial effects in various CNS injury models and neurodegenerative diseases. It provides choline for acetylcholine synthesis and stimulates dopamine release. Antioxidants like Vitamin C and E, known for mitigating oxidative stress, may enhance the nootropic effects of citicoline.

Method: ICR mice were trained for 4 days and then administered intraperitoneal doses of ketamine (50 mg/kg) for 8 days to induce cognitive impairment. Subsequently, the mice received oral doses of citicoline (30, 100, 300 mg/kg), Vitamin E (100, 200, 300 mg/kg), Vitamin C (100, 200, 300 mg/kg), or normal saline. Cognitive performance was assessed using the spontaneous alternation Y-maze test and the novelty object recognition test.

Results: Citicoline, Vitamin C, and Vitamin E all enhanced learning and memory, as evidenced by the increased percentage exploration of the novel object in the novelty object recognition test and higher percentage alternation in the Y-maze test, counteracting ketamine-induced cognitive impairment.