Isatou A. NYANG

• Monitored oncology clinical trials across phases, ensuring strict adherence to ICH-GCP, FDA, and sponsor protocols while maintaining patient safety and data integrity.
• Conducted study start-up through close-out activities including site selection, regulatory submissions, initiation visits, monitoring, and close-out visits.
• Collaborated with investigators, site staff, and cross-functional teams to resolve issues, support enrollment, and maintain compliance with timelines.
• Verified informed consent, adverse event reporting, and protocol deviations, ensuring accurate documentation within the trial master file (TMF).
• Identified and mitigated study risks, providing corrective actions and audit-ready documentation to support overall trial success.

• Performed routine checks and vital sign assessments, contributing to a patient-centric environment focused on recovery.
• Managed and organized patient documentation, maintaining compliance with health care standards and ensuring data accessibility.
• Supported the implementation of patient care strategies aimed at improving recovery outcomes and overall service quality.
• Performed administrative and process improvement tasks to support clinical operations and enhance team efficiency.

• Designed and optimized CRISPR-Cas9 guide RNAs and protocols to study gene function in cancer pathways.
• Applied cell culture, transfection, and molecular assays to assess editing efficiency, off-target effects, and functional outcomes.
• Gained expertise in genome engineering and functional genomics, supporting the advancement of targeted cancer therapies.

mtDNA Mutations in Cancer Proliferation & Progression

• Conducted research on mitochondrial DNA (mtDNA) mutations in cancer, investigating molecular alterations driving tumor development.
• Utilized molecular biology techniques (PCR, gel electrophoresis, DNA isolation/quantification) to analyze genetic mutations and biomarker patterns.
• Contributed to precision medicine approaches, reinforcing the role of molecular insights in linking targeted therapies to patients.